Evaluation of pinhole collimator materials for micron-resolution ex vivo SPECT
نویسندگان
چکیده
منابع مشابه
Evaluation of the performance of parallel-hole collimator for high resolution small animal SPECT: A Monte Carlo study
Introduction: Image quality and accuracy of in vivo activity quantification in SPECT are affected by collimator penetration and scatter components, especially in high energy imaging. These phenomena highly depend on the collimator characteristic and photon energy. The presence of penetrated and scattered photons from collimator in SPECT images degrades spatial resolution, contr...
متن کاملPerformance evaluation of a multi-pinhole collimator with vertical septa
The authors have previously reported a simulation study on a novel multi-pinhole (MP) collimator that is able to provide improved angular sampling and an enlarged imaging field of view (FOV) when compared to a low-energy high-resolution parallel-hole (LEHR) collimator using a detector of equivalent size. The aim of this study was to develop a miniature single photon emission computerized tomogr...
متن کاملHigh-resolution tomography of positron emitters with clustered pinhole SPECT.
State-of-the-art small-animal single photon emission computed tomography (SPECT) enables sub-half-mm resolution imaging of radio-labelled molecules. Due to severe photon penetration through pinhole edges, current multi-pinhole SPECT is not suitable for high-resolution imaging of photons with high energies, such as the annihilation photons emitted by positron emitting tracers (511 keV). To deal ...
متن کاملEvaluation of high-resolution pinhole SPECT using a small rotating animal.
UNLABELLED Ex vivo measurements in animals are used frequently in the field of nuclear medicine for the characterization of newly developed radioligands and for drug development. In vivo SPECT would replace these ex vivo measurements in a relatively large number of cases if one were able to adequately image small organs. The pinhole collimator has been used extensively to obtain greater detail ...
متن کاملGeometric Sensitivity of a Pinhole Collimator
Geometric sensitivity for single photon emission computerized tomography (SPECT) is given by a double integral over the detection plane. It would be useful to be able to explicitly evaluate this quantity. This paper shows that the inner integral can be evaluated in the situation where there is no gamma ray penetration of the material surrounding the pinhole aperature. This is done by converting...
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ژورنال
عنوان ژورنال: Physics in Medicine & Biology
سال: 2019
ISSN: 1361-6560
DOI: 10.1088/1361-6560/ab1618